Dr. rer. nat. Asma Siddique
Kontakt
siddique@pos.tu-...
work +49 6151 16-21928
fax +49 6151 16-21921
Work
L2|07 203
Peter-Grünberg-Straße 16
64287
Darmstadt
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| Oberflächenmodifizierung von PDMS-basierten mikrofluidischen Sytemen für verbesserte Zelladhäsion bei hohen Scherkräften |
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MF Kilb, VI Engemann, A Siddique, RW Stark, K Schmitz (2021): Immobilisation of CXCL8 gradients in microfluidic devices for migration experiments Colloids and Surfaces B: Biointerfaces 2021 198, 111498. DIO: https://doi.org/10.1016/j.colsurfb.2020.111498 [Artikel] |
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A Siddique, I Pause, S Narayan, L Kruse, RW Stark (2021): Endothelialization of PDMS-based microfluidic devices under high shear stress conditions Colloids and Surfaces B: Biointerfaces 2021 197, 111394 DOI: https://doi.org/10.1016/j.colsurfb.2020.111394 [Artikel] |
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MF Kilb, V Engemann, A Siddique, RWvStark, K Schmitz (2021) Immobilisation of CXCL8 gradients in microfluidic devices formigration experiments DOI: https://doi.org/10.1016/j.colsurfb.2020.111498 [Artikel] |
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Siddique, Asma ; Meckel, Tobias ; Stark, Robert W. ; Narayan, Suman : Improved cell adhesion under shear stress in PDMS microfluidic devices. [Online-Edition: http://dx.doi.org/10.1016/j.colsurfb.2016.11.011] In: Colloids and Surfaces B-Biointerfaces, 150 S. 456-464. ISSN 0927-7765 [Artikel] , (2017) |
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Siddique, Asma ; Gul, Ambreen ; Irfan, Muhammad ; Nadeem, Muhammad ; Syed, Quratulain Comparison of different pretreatment methods for efficientconversion of bagasse into ethanol [Online-Edition: DOI: 10.1080/17597269.2016.1215066] In: Biofuels, 8:1, 135-141 [Artikel], (2017) |
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Siddique, Asma ; Bashir, Aftab ; Latif, Farooq Exploration of unique relationamong industrial fungi by statistical analysis In: Songklanakarin J. Sci. Technol. 34(6), 607-613 [Artikel], (2012) |
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Khan, S.A. ; Siddique, A. ; Latif, F. Fibrolytic enzyme production fromHumicola insolens and its applications in animal feed In: Pakistan J. Zool. Suppl.Ser. 9:41-45 [Artikel], (2009) |
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Anwar, Farooq ; Siddique, Asma ; Iqbal, Shahid ; Asi, M. Rafique Stabilization of sunflower oil with Moringa oleifera leaves under ambient storage In: Journal of Food Lipids, 14: 35-49 [Artikel], (2007) |
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Siddique, A. ; Anwar, F. ; Manzoor, M. ; Fatima, A Antioxidant activity ofdifferent solvent extracts of Moringa oleifera leaves under accelerated storage of Sunflower oil In: Asian Journal of Plant Science, 4(6): 630-635 [Artikel], (2005) |
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Asma Siddique, Isabelle Pause, Suman Narayan and Robert W. Stark Stability of protein coatings inside microfluidic devices under flow conditions µFlu’18-NEGF’18, Feb. 2018, Strasbourg, Frankreich |
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Asma Siddique and Robert W. Stark Microfluidics; A competent analytical tool in life science Emerging trends in life sciences for sustainable development, Oct. 2014, Lahore Pakistan |
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Asma Siddique, Isabelle Pause, Suman Narayan and Robert W. Stark Stability of protein coatings inside microfluidic devices under flow conditions µFlu’18-NEGF’18, Feb. 2018, Strasbourg, Frankreich |
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Asma Siddique, Suman Narayan and Robert W. Stark Stable protein coating inside PDMS microfluidic devices for improved cell adhesion under shear stress Lab-on-Chip & Microfluidics 2017, May 2017, München, Deutschland |
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Asma Siddique, Suman Narayan and Robert W. Stark Stable protein coating inside PDMS microchannels for cell growth under flow conditions EMBL Conference, Microfluidics 2012, Jul. 2014, Deutschland |
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| Many of the vascular functions, hemodynamic forces, cellular interactions and related diseases are strictly related to of physical geometry of vasculature. Combination of microfluidics and cell biology offers a physiologically realistic platform to reproduce various vascular models in laboratory leading to better understandings about cell and tissue physiology in 3D environment. Under a shear flow, however, the stability of cells that were grown on physically adsorbed proteins is short lived, which limits long-term cell studies. Focusing on this issue various protein-substrate linkages were developed for stable cell growth under high flow conditions (at physiological shear stress in human vasculature). APTES (3-Aminopropyl)triethoxysilane is primarily used to immobilized collagen on PDMS surface for stable endothelial cells growth at long term, high shear stress. |